Anxiety and mood changes have been reported by some users
In a large 56-week clinical trial that evaluated liraglutide in individuals who were overweight or had obesity, as well as had diabetes or prediabetes, participants reported statistically significant weight loss compared with those who took the placebo at the end of the study
Hemoglobin A1c levels generally rise within weeks to months, returning toward pre-treatment values unless significant lifestyle changes have been maintained
Some clinical studies have shown that boosting protein during food intake may be helpful
One of those drugs, and currently its second biggest seller, is Stelara (ustekinumab), which is also going to be hit by its recent loss of exclusivity in the US
Injectable GLP-1 medications can be given at any time, but oral semaglutide (Rybelsus) also requires fasting administration, so consider bedtime levothyroxine dosing with careful TSH monitoring