Weekly injections of B12 over 24 weeks significantly improved neurological disability in patients with MS in a randomized controlled experiment, showing improvements after two weeks of treatment, which were further improved by the addition of lofepramine and l-phenylalanine [137]
Options for managing tolerance include a brief dose reduction for 4 to 8 weeks ("drug holiday" at a lower dose, not complete cessation), lifestyle optimization to maximize the medication effect, evaluation for other contributing factors (thyroid function, cortisol, sleep quality, medication interactions), and consideration of adding a complementary compound to address specific aspects of the plateau
Beneficiaries suffering from blood loss may also need an IV iron shot
[15] [16] Tests may include full blood count, serum B12 levels, anti-intrinsic factor antibodies (to diagnose pernicious anaemia), and sometimes methylmalonic acid or homocysteine levels when the diagnosis is uncertain
These shots are often viewed as a less invasive alternative to more aggressive weight loss interventions
Vitamin B12 by Jack Norris, RD Contents Essential Information Vitamin B12 is arguably the most important nutrient in vegan nutrition
