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The hypothesis proposes cells at risk of being driven into the IDO metabolic trap include antigen-presenting cells, serotonergic neurons in the midbrain raphe nuclei, serotonin-producing enterochromaffin cells in the intestinal mucosa, and melatonin-producing pinealocytes

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Yoshida H, Hara KY, Kiriyama K, Nakayama H, Okazaki F, Matsuda F, Ogino C, Fukuda H, Kondo A

Bhoyate A, Priya LR, Moirangthem GS (2024) Clinicopathological profile of hemorrhoids in north east India

doi: 10.1038/s41586-023-06651-y 98 KervevanJStaropoliISlamaDJeger-MadiotRDonnadieuFPlanasDet al

30 Failure rate PRP has become popular in sports medicine due to its ability to improve the healing capacity of wounded tissues