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Why does the article single out autonomic neuropathy as a risk factor

They are crucial mediators of local inflammation, and typically attract other proinflammatory cell types such as neutrophils and Th1 cells at later stages of inflammation (52)

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The subgroup of A-fibers plays a crucial role in respiratory regulation by transmitting important sensory information associated with the central inspiratory drive (Bozler and Burch 1951

Based on current UK guidance and product information, these medicines can generally be used concurrently under appropriate medical supervision