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It is important to note that whilst the injection itself may maintain adequate B12 levels for weeks to months, the clinical benefits such as improved energy, cognitive function, and resolution of neurological symptomsdepend on consistent maintenance of optimal levels

10.3390/ijms20071635 80 KimC

Success will depend on a balanced, iterative process: using clinical observations to inform targeted preclinical models, and using mechanistic insights from those models to design smarter, biomarker-enriched clinical trials

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