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The NRF2-Mediated Regulation of Lipid Metabolism in CLDs In addition to NRF2s primary function in regulating antioxidant pathways, it has also been shown to impact lipid metabolism, making it a topic of growing interest, especially in the context of CLDs [83,84]

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Serum AST and ALT tend to be normal or mildly elevated in patients with alcoholic liver disease but below 300 U/mL despite severe liver injury