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The relationship between diabetes medications and fluid balance requires careful clinical consideration, as some agents may worsen retention while others have neutral or potentially beneficial effects on fluid homeostasis

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Glucose dependent insulin and glucagon secretion Semaglutide lowers high blood glucose concentrations by stimulating insulin secretion and lowering glucagon secretion in a glucose-dependent manner

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The active ingredient in Wegovy (semaglutide) mimics the GLP-1 hormone that is naturally produced in the body, increasing feelings of fullness and slowing down the rate at which food leaves the stomach