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Clin Pharmacol Ther 1994;55(6):681-692

These findings suggest that the role of trypsin may be primarily to facilitate the release of CTSB into the cytosol, which helps explain why the inhibition of either CTSB or trypsin can prevent acinar cell death

In this Perspective, we summarize key trends in peptide drug discovery and development, covering the early efforts focused on human hormones, elegant medicinal chemistry and rational design strategies, peptide drugs derived from nature, and major breakthroughs in molecular biology and peptide chemistry that continue to advance the field

C., & Durmaz, R

28 CuiJ.ZhaiZ.WangS.SongX.QiuT.YuL.et al (2024)

In the past five years, these drugs have moved from diabetes clinics to mainstream medicine and for good reason