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Unlike master regulators such as PPAR, whose deletion leads to lipodystrophy and severe metabolic dysfunction, loss of GPR146 attenuates lipid accumulation without impairing early adipocyte commitment, resulting in smaller but histologically intact adipose depots

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Peng L, Liu Z, Xiao J, Tu Y, Wan Z, Xiong H, Li Y, Xiao W

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Acid-related complications after laparoscopic Roux-en-Y gastric bypass: risk factors and impact of proton pump inhibitors

As part of the deal, Caremark agreed to remove Zepbound from its commercial formulary