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Available at: Singh, P., et al

Impaired thyroxine and 3,5,3-triiodothyronine handling by rat hepatocytes in the presence of serum of patients with nonthyroidal illness

While those numbers are modest compared to GLP-1 agonists, the advantage of AOD-9604 is its targeted mechanism and favorable safety profile

For patients, the practical takeaway is straightforward: if your inflammation is closely tied to insulin resistance, central weight gain, fatty liver, or metabolic syndrome, a GLP-1 medication may help

It's also the first to map how each drug class shapes the natural history of Afib