function of l carnitine The Role L-Carnitine in Kidney Disease and Related Metabolic Dysfunctions Multiple metabolic actions of L-carnitine

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Cell 56 KozhukharN.AlexeyevM

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Current Medicinal Chemistry

In particular, instability of the linker and heterogeneity of the product (i.e., broad distribution of DARs) often negatively impacts ADC efficacy and therapeutic window, which often leads to difficulty or limitation in the optimization for clinical application and eventual failure in clinical trials

doi:10.1056/NEJM199410063311401 21