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Furthermore, long-term administration of compounds like Astragalus polysaccharides or palmitic acid can promote hepatic steatosis and chronic inflammation, the latter exacerbating toxicity through gut microbiota dysregulation (Ding et al., 2018

(2016) 311:F46986

Surprisingly, the nucleotide-binding oligomerization domain protein 2 (NOD2) functions as a receptor for pattern recognition

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Among ROS, H 2 O 2 is the only one able to cross the cellular membrane through the membrane water channels aquaporins and, therefore, to move with water in sites distant from that of its production [16,17]

Chi CC, Lee CY, Liu CY, Wang SH, Tien O'Donnell F, Tung TH