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5.2 Nanomaterial-based delivery systems and mitochondrial therapy Nanomaterials offer a powerful platform for precise mitochondrial-targeted therapy

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A new cytotoxic, DNA interstrand crosslinking agent, 5-(Aziridin-1-YL)-4-hydroxylamino-2-nitrobenzamide, is formed from 5-(Aziridin-1-YL)-2,4-dinitrobenzamide (CB 1954) by a nitroreductase enzyme in Walker carcinoma cells

Science 324 , 98102 (2009)

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