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Certain medications use sublingual delivery specifically to bypass first-pass metabolism in the liver

In this study, we aimed to clarify the association between endometriosis and perinatal complications and investigate whether there is a significant difference in the incidence of placenta previa depending on the degree of surgical completion of endometriosis before pregnancy

As it lacks antimicrobial agents, it is intended for single use

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N Engl J Med (2015) 373:24846