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Tesamorelin underwent pharmaceutical development for the specific indication of HIV-associated lipodystrophy, leading to Egrifta approval

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Their mean plasma ammonia concentration was within the normal range, but 24 patients (35.3%) with ammonia concentrations above 80 g/dl were considered hyperammonaemic and 15 of these 24 (22.1%) had ammonia concentrations above 100 g/dl