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Further, the SOLOIST-WHF trial108, although ended prematurely due to lack of funding, showed that sotagliflozin versus placebo was safe and beneficial in patients with diabetes and acute HF, irrespective of whether the patient had reduced or preserved ventricular function
The reductions in systolic blood pressure were consistent across subgroups of participants in the study who were categorized by additional factors, including age, sex, body mass index, and hypertension-related risk factors
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