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Differential expression analysis identified 14 upregulated and 15 downregulated proteins in polyps, while PCA demonstrated clear separation between polyp and gallstone samples, establishing distinct proteomic signatures

Satisfied with the results

Note: Abbreviations: SS, Sjogrens syndrome

References 1 RuscioAMSteinDJChiuWTKesslerRC

However, efficient and targeted intra-articular gene delivery remains a considerable technical challenge, primarily due to the dense extracellular matrix (ECM) of cartilage, rapid clearance of joint fluid, and limited cellular uptake

That's just not long enough to have a sustained therapeutic effect