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10.3390/MD19020113 37 ShimJ

Cancer cells utilize glutamine metabolism-related branched pathways involved in the development of drug resistance Glutamine synthetase (GS), an enzyme that functions at the origin of glutamine metabolism, is the sole regulatory factor that governs glutamine synthesis from its fundamental stages, thereby playing a pivotal role in the progression of cancer [213]

World J Urol 2019

Treatment may need to address: poor sleep ongoing nervous system activation burnout overtraining lack of recovery emotional stress that keeps the body in a reactive state For some patients, this is the missing link

Application can be increased to twice per day and gradually increase the time on the skin if well tolerated

& Cavallo, M