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Male B6.V-Lepob/JRj (ob/ob) mice were purchased from Cavens Experimental Center (Changzhou, China)

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In a study in patients with different degrees of hepatic impairment, no clinically relevant change in semaglutide pharmacokinetics was observed [see Clinical Pharmacology (12.3)]

Pipecolic acid modulates the YAP-GPX4 signaling pathway, reduces retinal vascular tube formation, and mitigates ferroptosis