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Medical Writing/Editorial Assistance The authors acknowledge Alice Knapton, PhD, Noa Chapman, MSc, and Arianna Psichas, PhD from Costello Medical, UK, for management of the Delphi panel, data analysis, medical writing, and editorial assistance based on the authors input and direction

With consumer-grade equipment and uncertain vial contents, hitting those targets precisely is extremely difficult

Precision without accuracy is worse than estimation

Purity, sterility, and the absence of endotoxins are not guaranteed in the same way they would be for a licensed medicine

Current Legal Status (As of 2026) As of early 2026, the legal status of compounded GLP-1 medications can be summarized as follows: Compounded semaglutide: The regulatory picture for compounded semaglutide is complex