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The N-terminal region typically contains the signal peptide, which is required for secretion of the mature effector protein from the pathogen into the host (Presti et al., 2015), as well as the translocation domain, which is required for the correct localisation of the effector into the host cell (Irieda et al., 2019)

doi: 10.3389/fendo.2023.1093691 9 JohannssonGTourainePFeldt-RasmussenUPicoAVilaGMattssonAFet al

Quick Answer: Yes, acetaminophen can deplete glutathione levels in the body

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Gyurszov M, Gureck R, Bbkov J, Tthov