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Supporting this link, studies in mammals show that S-nitrosylation of PDI by NO induces protein misfolding and neurodegeneration (Uehara et al

H., Cavaller-Bellaubi, M., Nishimura, Y

Meanwhile, pPICZA-CBBBP, and pPICZA-DSIP plasmids were also constructed by using the same way

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Drugs and Reagents Dihexa and wortmannin were purchased from MedChemExpress (Monmouth Junction, NJ, USA)