Neurochem Res 35:743748 Reuter SE, Evans AM (2012) Carnitine and acylcarnitines: pharmacokinetic, pharmacological and clinical aspects
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The FDA Shelf Life Extension Program tested primarily small-molecule drugs in solid dosage forms (tablets, capsules) for the military
These include: Persistent fatigue, cold intolerance, or constipation (suggesting hypothyroidism) Excessive thirst, increased urination, or blurred vision (indicating poor glycaemic control) Abdominal pain, nausea, or vomiting (potential pancreatitis, a rare but serious adverse effect) Right upper quadrant pain, jaundice, pale stools, or dark urine (possible gallbladder disease, which has increased risk with GLP-1 receptor agonists) [1] [2] New visual symptoms including floaters or blurred vision (potential diabetic retinopathy complications) Mood changes, particularly low mood or increased anxiety New or worsening oedema in the legs, ankles, or face Lack of expected weight loss after three to six months at therapeutic doses should also prompt discussion with your healthcare provider
Peritoneal taurolidine lavage in children with localized peritonitis due to appendicitis
GLP-1 and weight loss: unraveling the diverse neural circuitry
