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5.1.6 Nanoparticle-based ferroptosis therapies in OA Nanotechnology has emerged as a promising strategy for enhancing the targeting, efficacy, and bioavailability of ferroptosis-related therapeutics in OA

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For example, patients who combine nutraceuticals with anticoagulants may experience clotting modifications due to alterations in CYP enzyme activity (93, 96), necessitating regular coagulation monitoring on a weekly basis to ensure safety and efficacy

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Nutrient deficiencies, particularly vitamin D and selenium

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