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Patients experiencing episodic right upper quadrant discomfort, particularly after meals, should contact their healthcare provider within 24-48 hours

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Patients on azathioprine, 6-mercaptopurine, or TNF inhibitors require additional pharmacological interaction screening

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Cooperation between mitochondria and peroxisomes Previous studies in mammals and zebrafish have shown that when mitochondrial -oxidation is inhibited and fat accumulates in the liver or heart, CPT1 gene expression or enzyme activity compensatorily increases to enhance FA transport into the mitochondrial matrix ( Reference Li, Li and Qin 32 , Reference Degrace, Demizieux and Gresti 52 , Reference Degrace, Demizieux and Du 56 )