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The development history and clinical translation challenges of PROTAC The development history of PROTAC As an emerging TPD strategy, PROTAC technology harnesses the UPS to selectively degrade disease-associated proteins, offering a novel therapeutic modality for targets traditionally considered undruggable by conventional small molecules

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This potential application holds significant promise, particularly in sports medicine and rehabilitation, where it could potentially aid in the recovery of injuries and musculoskeletal conditions

These drugs have been shown not only to decrease the risk of development of cancer, but also decrease progression of known cancers

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