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In the STEP UP clinical trial, the 7.2-mg dose demonstrated a mean weight loss of 20.7% at 72 weeks, compared with a reduction of 17.5% with the previously approved semaglutide (Wegovy) injection (2.4 mg) and 2.4% with placebo

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Following homogenization, the samples were centrifuged at 5,000 g for 5 min and the resulting supernatants were collected

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