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Both molecules (0.110 M) stimulated the proliferation of keratinocytes in a dose dependent manner and resulted in changes in epidermal basal cells whose integrins and p63 expression markedly increased

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396 Notably, the ABCG2 Arg141Lys variant has been consistently linked with poor response to allopurinol across multiple independent cohorts

The studies summarized below are presented with these contextual limitations made explicit