In the hindbrain, the dorsal-vagal-complex (DVC), collectively comprised of the nucleus tractus solitarius (NTS), area postrema (AP) and dorsal motor nucleus of the vagus (DMV), mediates the anorectic effects of both amylin and GLP-1 receptor agonists 15,16,17,18,19
Common issues include: Nasopharyngitis and upper respiratory tract infections : Reported more frequently than with placebo, though causality remains unclear
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Delivering for patients
This connection between appetite suppression and thirst suppression means that as your medication successfully reduces your desire for food, it's simultaneously reducing your body's signals to drink fluids
Below, experts walk us through the science of GLP-1s: where it began, what weve learned and where the field is headed next