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Nature 405, 180183

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Damage to the lining of the stomach and small intestine results in symptoms that range from relatively minor heartburn, nausea, and abdominal pain (affecting 15-40% of NSAID users) to the life-threatening ulceration, perforation, and bleeding (affecting 1-2% of chronic NSAID users) (Vonkeman 2010)

For broader context on how GI side effects connect and share underlying causes, the Ozempic and bloating article covers the shared mechanisms at play across most GI symptoms on GLP-1 treatment

This helps people avoid overeating by increasing feelings of fullness

Some plans may cover these treatments when prescribed for a qualifying diagnosis such as obesity (BMI 30) or overweight (BMI 27) with a weight-related comorbidity