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This leaves us vulnerable to weakened immunity, thyroid issues, increased oxidative stress, and cancer risk

Neurochem Int 37:199

I am not sure about this finding but maybe its an evidence of decreased scar tissue and increased type 1 collagen

The MTHFD2 encoded enzyme is an NAD + /NADP + -dependent enzyme that possesses 5,10-methylene-THF dehydrogenase and 5,10-methenyl-THF cyclohydrolase activities