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Although the clinical impact of AATD in AAV is not yet fully understood, the American Thoracic Society/European Respiratory Society recommends assessing A1AT levels in cases of anti-PR3 vasculitis (98)
Animal studies support its potential for fat reduction
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Assessed were the inferior caval vein (which was occluded), right ovarian vein (which appears as blind vessel due to the infrarenal occlusion), and left ovarian vein (which serves as a bypassing pathway) (Vukojevic et al., 2018)
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