& Fraaije, J
66 Targeting multiple peptide hormone receptors with the same drug entity appears to be the most promising strategy, where additive, or even synergistic, benefits of simultaneously activating two receptor signalling pathways in bone can be fully realised
Retatrutide is a GGG tri-agonist peptide developed for the simultaneous activation of the GLP-1, GIP, and glucagon receptors
Because retatrutide is an investigational medicinal product (IMP) that has not received a marketing authorisation in the UK, there is no approved prescribing information or patient dosing schedule
Encouragingly, ongoing trials, such as EVOKE and EVOKE+, are already exploring this potential for early Alzheimer's disease
This practice is essential because the in-use time limit takes precedence over the printed expiration date