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[2] [11] As of 2026, retatrutide has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA), and it remains an experimental compound available only within authorised clinical trial settings

Once reconstituted, solutions should be aliquoted into single-use volumes and stored at -20C

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Other populations at risk include people who had gastrointestinal surgery (including weight loss surgery) and diseases that affect the gut, such as Crohn's disease or celiac disease