Studies have shown that particles with polar functional groups, such as carboxyl or amino groups, more readily bind to regions of cell membranes with opposite charges and are internalized through phagocytosis [22, 23]
Sometimes it's used appropriately
Meaningful weight loss typically begins at the 4mg dose (week 5-8), accelerates at 8mg (week 12-16), and reaches peak effect at 12mg after 24+ weeks
Quesada O et al
However, if your body is constantly running a process called adipogenesis, you are fighting an uphill battle because you are physiologically recruiting more storage space
Accordingly, maintenance of a healthy mitochondrial network, defined as mitochondrial homeostasis, is critical for normal mitochondrial function during development and even throughout life