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Although its known that exercise protects against CVD by reducing sympathetic impulses, arterial pressure, and heart rate, increasing blood flow and endothelial NO production, causing vessel dilation, and decreasing inflammatory cytokines and oxygen radical formation, the precise processes that lead to transcriptional factor modifications are unknown

This mitochondrial dysfunction may lead to arrest of cell division, triggered by OS [15, 16]

They offer a systemic approach, meaning they address symptoms throughout the body

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