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For example, Merck markets combination pills (like Janumet) and XR formulations to extend revenue, and Novo Nordisk has Ongoing label expansions for its semaglutide line

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This highlights the importance of long-term planning

PDE5 inhibitors and PT-141 are generally safe for most people, but there are important contraindications and cautions: PDE5 inhibitors should not be taken by individuals using nitrates (e.g., nitroglycerin) due to the risk of severe hypotension (low blood pressure)

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