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(10) Studies conducted while observing research models impacted by obesity indicate that Frag 176-191 experimentation may restore mitigated 3-AR levels to those similar to control models

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Regular monitoring and appropriate dose adjustment of levothyroxine to maintain TSH within the reference range (typically 0.4-4.0 mU/L, though individualised targets may apply) is essential before implementing additional weight management interventions

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For best results, GLP-1 patches should typically be used daily