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Go to urgent care or an emergency department if: abdominal pain is severe or localized to the right upper quadrant, you develop fever above 38.5C with GI symptoms, you notice yellowing of the skin or eyes, urine turns dark brown with pale stools, or heart rate exceeds 110 at rest without other explanation

Less common, but more severe side effects that have been reported include gallbladder and pancreas problems

they work best as part of a comprehensive approach including dietary modification and physical activity

doi: 10.1016/j.ejphar.2012.12.012 143 McCleanPLJalewaJHolscherC

They do not require the same abdominal incisions used in traditional bariatric surgery

High-fat meals may worsen gastrointestinal discomfort for some patients