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In the positive control analysis, effect of GLP-1R expression on T2D and BMI were estimated

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First, it reduces the bladder effective capacity, meaning you feel the urge to urinate more frequently but with smaller volumes

Moreover, due to the reconstruction of context-specific models for hundreds of thousands of cells being a limiting step in our analysis, we based our approach on Recon2.2 19 which is much smaller in size than more current reconstructions of human metabolism, like Recon3D 77

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