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While its effective for managing type 2 diabetes, its important to keep in mind that it isnt suitable for type 1 diabetes

GLP-1 receptor stimulation (e.g., through GLP-1 (33) prevents ROS and reduces vascular oxidative stress

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For example, in the study we cited where berberine went up against metformin, 35% of subjects had significant gastrointestinal upset when taking the 1,500 mg/day dose (three capsules worth)

3q), suggesting that these animals are sensitised to GLP-1R agonism, supporting our previous observation that sensitivity to GLP-1R agonism is enhanced in mice lacking Gipr in the hypothalamus 7