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*Correspondence: Juan Huang, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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A stable cell population with genomically integrated switch components was generated, and high-performing clones were identified based on nLuc expression and fold induction (Supplementary Fig