Rahman et al
Lower cagrilintide doses in combinations When combining, can reduce cagrilintide: 1.8mg cagrilintide + 2.4mg semaglutide: Still very effective (14-18% weight loss estimated) Better tolerated than both at 2.4mg Cost savings on cagrilintide Consider if GI-sensitive 1.2mg cagrilintide + 2.4mg semaglutide: Modest benefit from cagrilintide addition Minimal GI side effects from cagrilintide Semaglutide does heavy lifting May still achieve 12-15% total weight loss Testing approach: Start with standard doses (both 2.4mg) If intolerable, reduce cagrilintide first Maintain semaglutide at 2.4mg (well-tolerated, established) Find optimal cagrilintide dose for your tolerance Maintenance dosing after weight loss Strategies to sustain results long-term
Origin: Synthetic growth hormonereleasing peptide (GHRP class)
Nutrients known to support gut heath, mucus production, support tight junctions and secretory immunoglobulin type A (SIgA) levels include: L-glutamine fuels gut cells and boosts immunity Coconut oil/MCTs antibacterial/antifungal Bone broth / gelatine / collagen Vitamins D3 and A increase SigA Aloe vera/liquorice/quercetin Digestive enzymes Apple cider vinegar / betaine HCl supplements/high dose ascorbic acid increase natural stomach acid N-acetyl glucosamine anti-inflammatory, helps protect the lining of the stomach and intestines FMS may present with protein malabsorption issues FMS patients appear to have low BCAA (leucine, isoleucine, and valine) Diet and lifestyle The diet recommended to those with fibromyalgia should consist of simple, healthy and unadulterated foods, with junk foods and foods that are processed and highly refined being completely eliminated, as they are commonly linked to the triggering of symptoms
Physical activity and diet shape the immune system during aging
Aescin also has intriguing neuroprotective capabilities through its anti-inflammatory and antioxidant actions 137
