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Severe or blood glucose confirmed symptomatic hypoglycemia (glucose of 56 mg/dL or less) was not reported in any of the patients receiving semaglutide monotherapy compared to 1.6% of patients receiving placebo

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If patients do experience headaches, chest tightness, or dizziness during an NAD+ infusion, it is often relieved by pausing or slowing the infusion rate

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Extended protocols may be appropriate for individuals with significant body composition goals, those who respond gradually to therapy, or patients seeking comprehensive metabolic optimization under close medical supervision