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Although an inflammatory phenotype was not detected in the brain, systemic immune dysregulation was suggested by significant decreases of IFN, TNF, IL-1, and IL10 (Zakirova et al., 2017)

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Accordingly, in many individuals, whether healthy or with diabetes, a 75 g oral glucose load (~1255 kJ), as in an OGTT, will not have emptied completely from the stomach at 120 min (as this would require an emptying rate 11 kJ/min) [7] (Fig

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