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Cells were disrupted using an Emulsiflex instrument (Avestin) and cleared by centrifugation

Sue facilitates cardiology bookings and can be contacted on [email protected] Phone: 07472 350470 Andrew Paul Preston BSc (Hons), MSc, British Society Accrediated ECHO-physiologist Andy has trained in echocardiography at the Bristol Heart Institute and is accredited by the British Society of Echocardiography (BSE)

The levels of cell cycle inhibitors P21 CIP1 and P27 Kip1 were also altered in Gstp1/2 / reinforcing the conclusion of an impaired progression in G1 phase in mutant mice (Figure 5c)