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Dehydration is a primary concern when diarrhea occurs, making fluid and electrolyte replacement an important part of symptom management

However, Abbas et al

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Staying properly hydrated while taking GLP-1 medications like semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound) is essential for managing side effects and optimizing treatment outcomes

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Moreover, the SURMOUNTMMO (tirzepatide, NCT05556512) will assess the impact of the dual GLP-1/GIP RA in cardiovascular outcomes and all-cause mortality for people with obesity (without diabetes) when the REDEFINE-3 study will assess the impact of cagrisema in people with obesity (with and without T2DM) and established cardiovascular disease