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Federal Trade Commission (FTC) announced that a company that heavily advertised an herbal dietary supplement called "Sagee" to the Chinese-language and Vietnamese-language communities had settled FTC charges of making false and unsubstantiated claims for the product

Red flag symptoms requiring immediate medical attention include severe pain, blood in vomit or stool, unexplained weight loss over 10 pounds, or difficulty breathing while lying down

Potential concerns include: Unknown product quality Contamination or sterility issues Incorrect dosing Injection site reactions Allergic or immune reactions Medication interactions Hormonal or metabolic effects Unclear long-term safety Lack of monitoring Delayed treatment for an actual injury or medical condition Medical oversight is especially important for patients with autoimmune conditions, cancer history, active infections, chronic inflammatory disorders, cardiovascular concerns, hormone-sensitive conditions, or complex medication regimens

Chan School of Public Health: "Vitamin B12." Inflammatory Bowel Diseases: "Prevalence of and risk factors for vitamin B(12) deficiency in patients with Crohn's disease," "Vitamin B12 deficiency in inflammatory bowel disease: prevalence, risk factors, evaluation, and management." MedlinePlus: "Cyanocobalamin Injection." National Health Services: "Hydroxocobalamin," "Treatment -Vitamin B12 or folate deficiency anaemia Contents," "Vitamin B12." Nutrition Reviews: "How prevalent is vitamin B(12) deficiency among vegetarians?" Surgery for Obesity and Related Diseases: "Vitamin B12 deficiency in patients undergoing bariatric surgery: preventive strategies and key recommendations." The American Journal of Clinical Nutrition: "How common is vitamin B-12 deficiency?" The American Journal of Gastroenterology: "Vitamin B12 deficiency in untreated celiac disease." Top B12 Injections Who Get Them, How Quickly They Work Related Articles 22 Healthy Foods High in B VitaminsAny deficiency of B vitamins can lead to various health conditions

For example, by using changes in body temperature to trigger the release of drugs, personalized disease treatment can be achieved

doi: 10.1126/SCISIGNAL.AAR3083 94 ShapiroMRYehWILongfieldJRGallagherJInfanteCMWellfordSet al