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Efficacy and safety of switching to Pasireotide in patients with acromegaly controlled with pegvisomant and first-generation somatostatin analogues (PAPE Study)

In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients receiving high doses of diuretics, symptomatic hypotension may occur in patients receiving angiotensin receptor blockers

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In addition, at 5 years, significantly fewer GLP-1 drug users (13.5%) than nonusers (19.9%) had died, for a 31% lower mortality risk with GLP-1 drug use (aSHR = 0.69

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Avoid harsh scrubbing, as it can irritate the skin