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Instead of typical functional polymorphisms in the coding region of IGF-1R gene, recent studies aimed to identify novel genetic variants located in untranslated regions (UTRs), such as miRNAs binding sites, that could potentially regulate the expression patterns of IGF-1R

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For example, Shi et al

The correlation analysis indicated that the basal (prior to irradiation) pulmonary levels of GPx2 mRNA as well as GPx activity positively correlated with the post-irradiation asymptomatic survival time of mice